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Brain & Spinal Cord Tumor Clinical Trials in Georgia

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.
Cancer Type = Brain & Spinal Cord Tumor
Cancer Type = Brain & Spinal Cord Tumor
NCI ID Cancer Type Trial Name
There are currently 51 active Brain & Spinal Cord Tumor clinical trials in Georgia.
NCI ID Cancer Type Trial Name
1.
9-ING-41 in Pediatric Patients With Refractory Malignancies.
Cancer Type
Brain & Spinal Cord Tumor, Hematopoietic Malignancies, Lymphoma, Neuroblastoma
NCT ID
NCT04239092
Protocol IDs
1902
NCI-2020-04584
2.
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT03093116
Protocol IDs
CA127-1024
NCI-2017-00648
CA127-1024
TPX-0005-01
Treatment Sites (1)
University Cancer and Blood Center, LLC - Athens Medical Oncology
Athens
3.
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)
Cancer Type
Brain & Spinal Cord Tumor, Colon/Rectal Cancer, Head and Neck Cancer, Lung Cancer, Neuroendocrine Tumor, Solid Tumor, Thyroid Cancer, Unknown Primary
NCT ID
NCT03157128
Protocol IDs
LOXO-RET-17001
NCI-2017-00976
2017-000800-59
Treatment Sites (1)
Emory University School of Medicine
Atlanta
4.
A Study of the Drug Selinexor with Radiation Therapy in Patients with Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor
NCT ID
NCT05099003
Protocol IDs
ACNS1821
ACNS1821
NCI-2021-11337
5.
A Study of the Drugs Selumetinib versus Carboplatin/Vincristine in Patients with Neurofibromatosis and Low-Grade Glioma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT03871257
Protocol IDs
ACNS1831
ACNS1831
NCI-2019-01396
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
6.
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients with Low-Grade Glioma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor
NCT ID
NCT04166409
Protocol IDs
ACNS1833
ACNS1833
NCI-2019-07600
7.
A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients with Recurrent Glioma with Elevated Mutational Burden
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04145115
Protocol IDs
A071702
A071702
NCI-2019-07242
8.
A Study to Compare Treatment with the Drug Selumetinib Alone versus Selumetinib and Vinblastine in Patients with Recurrent or Progressive Low-Grade Glioma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Unknown Primary
NCT ID
NCT04576117
Protocol IDs
ACNS1931
ACNS1931
NCI-2020-07549
9.
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT03970447
Protocol IDs
GCAR-7213
NCI-2019-04788
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
10.
Abemaciclib and Radiation Therapy in Treating Younger Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma, Recurrent or Refractory Solid Tumors, or Malignant Brain Tumors
Cancer Type
Brain & Spinal Cord Tumor, Neuroblastoma, Sarcoma
NCT ID
NCT02644460
Protocol IDs
AFLACST1501
NCI-2015-02256
IRB00083793
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
11.
An Investigational Imaging Technique (Quantitative Oblique Back Illumination Microscopy) during Brain Surgery for the Detection of Brain Tumors and Brain Tumor Margins
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor
NCT ID
NCT05513859
Protocol IDs
WINSHIP5571-22
NCI-2022-06212
STUDY00004168
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
12.
Cabozantinib and Isotretinoin in Treating Children with Relapsed or Refractory Solid Tumors
Cancer Type
Brain & Spinal Cord Tumor, Solid Tumor, Unknown Primary
NCT ID
NCT03611595
Protocol IDs
171971
NCI-2018-02497
13.
Childhood Cancer Survivor Study
Cancer Type
Brain & Spinal Cord Tumor, Hodgkin Lymphoma, Leukemia, Lymphoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Solid Tumor
NCT ID
NCT01120353
Protocol IDs
CCSS
U24CA055727
Treatment Sites (2)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
Aflac Cancer and Blood Disorders Center of Children’s at Scottish Rite
Atlanta
Karen Querubin, BSN
404-785-2215
14.
Comparing the Addition of Radiation either before or after Surgery for Patients with Brain Metastases
Cancer Type
Brain & Spinal Cord Tumor, Unknown Primary
NCT ID
NCT05438212
Protocol IDs
NRG-BN012
NRG-BN012
NCI-2022-04804
Treatment Sites (1)
Piedmont Columbus Regional
Columbus
15.
CX-4945 in Treating Patients with Recurrent SHH Medulloblastoma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Unknown Primary
NCT ID
NCT03904862
Protocol IDs
PBTC-053
PBTC-053
NCI-2019-00180
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
16.
Dabrafenib Combined with Trametinib after Radiation Therapy in Treating Patients with Newly-Diagnosed High-Grade Glioma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor
NCT ID
NCT03919071
Protocol IDs
ACNS1723
ACNS1723
NCI-2019-02289
Treatment Sites (1)
Curtis and Elizabeth Anderson Cancer Institute at Memorial University Medical Center
Savannah
Joni N. Shortt, RN, BSN, CCRC
912-350-8913
17.
Ensartinib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Solid Tumor, Wilms Tumor
NCT ID
NCT03213652
Protocol IDs
APEC1621F
APEC1621F
APEC1621F
NCI-2017-01243
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
18.
Genetic Testing in Guiding Treatment for Patients with Brain Metastases
Cancer Type
Brain & Spinal Cord Tumor, Solid Tumor, Unknown Primary
NCT ID
NCT03994796
Protocol IDs
A071701
A071701
NCI-2019-00744
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
19.
Hypofractionated Proton or Photon Radiation Therapy for the Treatment of Brain Tumors, the HiPPI Study
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04278118
Protocol IDs
RAD4811-19
NCI-2019-06446
IRB00114529
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
20.
Identification of Treatment Concentrations of Defactinib or Avutometinib for the Treatment of Patients with Glioblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT05798507
Protocol IDs
WINSHIP5751-22
NCI-2023-00602
STUDY00004876
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
21.
Immunotherapy (Nivolumab and Ipilimumab) for the Treatment of Relapsed or Refractory INI-1 Negative Cancer
Cancer Type
Brain & Spinal Cord Tumor, Hematopoietic Malignancies, Sarcoma
NCT ID
NCT04416568
Protocol IDs
20-041
NCI-2020-04573
22.
Informational Meetings for Planning and Coordinating Treatment, The IMPACT Trial
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Sarcoma, Solid Tumor
NCT ID
NCT04330833
Protocol IDs
IUSCC-0705
NCI-2021-01462
23.
Natural Progesterone for the Treatment of Recurrent Glioblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT05091866
Protocol IDs
WINSHIP5184-20
NCI-2021-01498
STUDY00002155
24.
NCORP Trial
Observation or Radiation Therapy in Treating Patients with Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT03180268
Protocol IDs
NRG-BN003
NCI-2016-01619
Treatment Sites (17)
Atlanta Cancer Care - Alpharetta
Alpharetta
Kristin Sieverding
770-777-1315
Atlanta Cancer Care - Conyers
Conyers
404-303-3355
Atlanta Cancer Care - Cumming
Cumming
404-303-3355
Atlanta Cancer Care - Decatur
Decatur
404-303-3355
Atlanta Cancer Care - Stockbridge
Jonesboro
Andrena Jefferson
678 466-2069
Atlanta Cancer Care - Tower
Atlanta
404-303-3355
Emory Saint Joseph's Hospital
Atlanta
Georgia Cancer Specialists - Athens
Athens
Cynthia Pirkle
Georgia Cancer Specialists - Canton
Canton
Georgia Cancer Specialists - CenterPointe
Sandy Springs
Anila Lokhandwala
404-256-4777 ext 9242
Georgia Cancer Specialists - Decatur
Decatur
404-303-3355
Georgia Cancer Specialists - Kennestone
Marietta
Greta Dudley
Georgia Cancer Specialists - Macon-Coliseum
Macon
Sonia Hernandez
478-745-6130 x8152
Northside Hospital Cancer Institute
Atlanta
Northside Hospital Central Research Department
404-303-3355
Piedmont Fayette Hospital
Fayetteville
404-851-2340
Winship Cancer Institute of Emory University
Atlanta
25.
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT05580562
Protocol IDs
ONC201-108
NCI-2023-02479
26.
ONC206 for the Treatment of Newly Diagnosed or Recurrent Diffuse Midline Gliomas or Other Recurrent Primary Malignant Central Nervous System Tumors
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04732065
Protocol IDs
200814
NCI-2021-00046
20-32465
PNOC023
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
27.
Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients with Recurrent or Progressive Grade 2 or 3 Meningioma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT02847559
Protocol IDs
NU 16C02
NCI-2016-01026
STU00203030
Treatment Sites (1)
Piedmont Healthcare
Atlanta
28.
Optune Delivered Electric Field Therapy in Treating Children with Recurrent, Progressive, or Refractory High-Grade Glioma or Supratentorial Ependymoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT03033992
Protocol IDs
PBTC-048
PBTC-048
NCI-2016-00926
PBTC-048
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
29.
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04049669
Protocol IDs
GCC1949
NCI-2019-08285
R01CA229646
Treatment Sites (2)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
Augusta University Medical Center
Augusta
Carol Terry
706-721-4430
30.
Peginterferon alfa-2b in Treating Younger Patients with Recurrent or Refractory and Radiographically or Clinically Progressive Pilocytic Astrocytomas and Optic Pathway Gliomas
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Cancer-Related Syndrome, Unknown Primary
NCT ID
NCT02343224
Protocol IDs
IRB00074563
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
31.
Pembrolizumab in Treating Younger Patients with Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT02359565
Protocol IDs
PBTC-045
PBTC-045
NCI-2015-00130
PBTC-045
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
32.
Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumors
Cancer Type
Brain & Spinal Cord Tumor, Head and Neck Cancer, Kidney Cancer, Lung Cancer, Melanoma, Ovarian Cancer, Solid Tumor, Unknown Primary
NCT ID
NCT05098132
Protocol IDs
STK-012-101
NCI-2022-00633
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
33.
Poly ICLC for the Treatment of Progressive or Recurrent Low-Grade Gliomas in Children and Young Adults with Neurofibromatosis Type 1
Cancer Type
Brain & Spinal Cord Tumor, Cancer-Related Syndrome, Unknown Primary
NCT ID
NCT04544007
Protocol IDs
NF111
NCI-2022-03434
34.
Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
Cancer Type
Brain & Spinal Cord Tumor, Unknown Primary
NCT ID
NCT04365374
Protocol IDs
GTM-102
NCI-2021-03480
35.
NCORP Trial
Project: Every Child for Younger Patients with Cancer
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Leukemia, Neuroendocrine Tumor, Solid Tumor, Unknown Primary
NCT ID
NCT02402244
Protocol IDs
APEC14B1
NCI-2014-02057
Treatment Sites (2)
Atrium Health Navicent
Macon
Oncology Research Nurse
4786332152
Augusta University Medical Center
Augusta
Carol Terry
706-721-4430
36.
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients with Newly Diagnosed WNT-Driven Medulloblastoma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Unknown Primary
NCT ID
NCT02724579
Protocol IDs
ACNS1422
ACNS1422
NCI-2016-00150
ACNS1422
Treatment Sites (1)
Curtis and Elizabeth Anderson Cancer Institute at Memorial University Medical Center
Savannah
Joni N. Shortt, RN, BSN, CCRC
912-350-8913
37.
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04427384
Protocol IDs
GTM-101
NCI-2020-13272
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
38.
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients with Brain Tumors
Cancer Type
Brain & Spinal Cord Tumor, Unknown Primary
NCT ID
NCT04908709
Protocol IDs
RAD4500-18
NCI-2018-02065
IRB00106849
39.
Standard Chemotherapy in Treating Young Patients with Medulloblastoma or Other Central Nervous System Embryonal Tumors
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Neuroblastoma, Neurologocal Tumor
NCT ID
NCT02875314
Protocol IDs
NCH-15004
NCI-2016-01993
IRB15-00399
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
40.
Stereotactic Radiosurgery or Hippocampus Avoidance Whole-Brain Radiation Therapy with Memantine in Treating Patients with 5 or more Brain Metastases
Cancer Type
Brain & Spinal Cord Tumor, Unknown Primary
NCT ID
NCT03550391
Protocol IDs
CCTG CE.7
CE.7
CCTG CE.7
NCI-2018-00395
Treatment Sites (2)
Emory Saint Joseph's Hospital
Atlanta
Winship Cancer Institute of Emory University
Atlanta
41.
Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)
Cancer Type
Brain & Spinal Cord Tumor, Hematopoietic Malignancies, Lymphoma, Unknown Primary
NCT ID
NCT04947319
Protocol IDs
ONO-4059-09
NCI-2021-14196
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
42.
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Wilms Tumor
NCT ID
NCT03155620
Protocol IDs
APEC1621SC
APEC1621SC
NCI-2017-01251
APEC1621SC
Treatment Sites (1)
Curtis and Elizabeth Anderson Cancer Institute at Memorial University Medical Center
Savannah
Joni N. Shortt, RN, BSN, CCRC
912-350-8913
43.
Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors that have Returned after Previous Treatment
Cancer Type
Brain & Spinal Cord Tumor, Unknown Primary
NCT ID
NCT05432804
Protocol IDs
10505
10505
NCI-2022-05066
PHII-222
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
44.
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT05095376
Protocol IDs
NRG-BN011
NRG-BN011
NCI-2021-10331
Treatment Sites (1)
Augusta University Medical Center
Augusta
Carol Terry
706-721-4430
45.
Testing the Safety and Benefit of Adding Hydroxychloroquine to Dabrafenib and/or Trametinib in Children with Recurrent or Progressive Low Grade or High Grade Brain Tumor with Specific Genetic Mutations
Cancer Type
Brain & Spinal Cord Tumor, Cancer-Related Syndrome, Unknown Primary
NCT ID
NCT04201457
Protocol IDs
PBTC-055
PBTC-055
NCI-2019-06216
46.
Testing the Safety, Tolerability and Immunological Effects of SurVaxM in Children and Young Adults with Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor
NCT ID
NCT04978727
Protocol IDs
PBTC-060
PBTC-060
NCI-2021-07694
47.
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
Cancer Type
Brain & Spinal Cord Tumor, Brain Tumor, Kidney Cancer, Sarcoma, Solid Tumor
NCT ID
NCT05286801
Protocol IDs
PEPN2121
PEPN2121
NCI-2022-01992
48.
Tumor Treating Fields for the Treatment of Brainstem Gliomas
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT05310448
Protocol IDs
WINSHIP5412-21
NCI-2021-09679
STUDY00003027
Treatment Sites (1)
Winship Cancer Institute of Emory University
Atlanta
49.
Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04590664
Protocol IDs
WINSHIP5070-20
NCI-2020-05187
50.
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients with Progressive Meningiomas
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT02523014
Protocol IDs
A071401
NCI-2015-00546
NCI-2015-00501
Treatment Sites (2)
Emory University Hospital - Midtown
Atlanta
Scott Edelman
404-686-4411
Winship Cancer Institute of Emory University
Atlanta
51.
WP1066 for the Treatment of Recurrent or Refractory and Progressive Malignant Brain Tumors
Cancer Type
Brain & Spinal Cord Tumor
NCT ID
NCT04334863
Protocol IDs
AFLACST1901
NCI-2020-07428
IRB00113194
Treatment Sites (1)
Aflac Cancer and Blood Disorders Center of Children’s at Egleston
Atlanta
Howard M. Katzenstein, MD
404-785-0853
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